Figure_8.tif (166.91 kB)
Quasispecies breadth is lower in relapser than nonresponder sequences.
figure
posted on 2008-05-07, 00:39 authored by Nathan A. Cannon, Maureen J. Donlin, Xiaofeng Fan, Rajeev Aurora, John E. TavisNonresponder and relapser sequences were analyzed using Phred and positions at which the dominant nucleotide was present at <80% frequency were determined. A) Number of positions of quasispecies diversity in nonresponders and relapsers in pre- and post-therapy samples. B) Proportion of positions of mixed nucleotides in post-therapy samples relative to pre-therapy samples. One nonresponder (3.22) and one relapser (10.00) are not shown. The relapser is the same as was removed from Figure 3A.