Fig_4.tif (633.84 kB)
Quantitative PCR of mutant and wildtype hypertrophic zones.
figure
posted on 2015-09-15, 03:14 authored by Trevor L. Cameron, Katrina M. Bell, Irma L. Gresshoff, Lisa Sampurno, Lorna Mullan, Joerg Ermann, Laurie H. Glimcher, Raymond P. Boot-Handford, John F. BatemanqPCR with primers specific for (A) Agc1, (B) Ctgf, (C) Matn1, (D) Creld2, (E) Derl3, (F) Ero1l, (G) Fgf21, (H) Steap1, and (I) p58IPK on cDNA derived from Wt, Xbp1CartΔEx2, ColXN617K and C/X hypertrophic zone aRNA. Plots depict mean fold differences with standard deviation from the mean, N = 3, statistical significance was determined using Student’s t test, ** p < 0.01, *** p < 0.001, **** p < 0.0001.
History
Usage metrics
Categories
Keywords
Disease Schmid metaphyseal chondrodysplasiacanonical ER stress sensorsXBPexogenous misfolding proteinchopperkhypertrophic zone collagenGADDchondrocyte differentiationhypertrophic chondrocytesupratfCol 10a Mouse models phenocopying MCDSpathologyColXN 617Kgrowth plate cartilage hypertrophic zone expansionhypertrophic zone cartilagehypertrophic zone expansionirerunx
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC