Figure_4.tif (1.57 MB)
PTX distribution in melanoma xenografts.
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posted on 2013-08-26, 01:36 authored by Lavinia Morosi, Pietro Spinelli, Massimo Zucchetti, Francesca Pretto, Andrea Carrà, Maurizio D’Incalci, Raffaella Giavazzi, Enrico DavoliTreated with vehicle (control, CTRL), 60 mg/kg, pretreated (5×8 mg/kg)+single dose (60 mg/kg) melanoma. Optical image in upper panels, distribution of PTX (ion m/z 284.2) in middle panels and internal standard, spotted 5 pmol/mm2 on tissue, in lower panels (ion m/z 289).
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BiochemistrymetabolismBiological transportModel organismsAnimal modelsmouseAnalytical chemistryChemical analysissignal processingImage processingDrugs and devicespharmacokineticsDrug distributiononcologyBasic cancer researchTumor physiologyCancer treatmentChemotherapy and drug treatmentCancers and neoplasmsSkin tumorsMalignant melanomamelanoma
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