Public Library of Science
Browse
Figure_4.tif (524.1 kB)

PBA inhibits other Kv channels.

Download (0 kB)
figure
posted on 2013-02-21, 07:08 authored by Karen Mruk, William R. Kobertz

(A) Time course of Shaker (inactivation removed) current measured in ND96 at +40 mV, 100 ms pulse when 10 mM PBA was applied through the bath solution. (B) Families of Shaker currents recorded before and during treatment with PBA. Currents were elicited by 100 ms step test potentials from −100 to +60 mV in 10 mV increments from a holding potential of −80 mV. Dashed line indicates zero current. Scale bars represent 1 µA and 0.1 s. (C) Time course of hERG current measured in ND96 at 0 mV, 2 s pulse when 10 mM PBA was applied through the bath solution. (D) Families of hERG currents recorded before and during treatment with PBA. Currents were elicited by 2 s step test potentials from −100 to +60 mV in 10 mV increments from a holding potential of −80 mV. Dashed line indicates zero current. Scale bars represent 1 µA and 0.5 s.

History

Usage metrics

    PLOS ONE

    Keywords

    Licence

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC