Orbital of locomotor activity in light and dark boxes.

(A) Typical traces of WT (left five, Wt) and Snap25S187A/S187A mice (right five, Hm) during 30 min. (B) % time in dark room. (C) Average moving velocity. (D) Latency to enter dark box. (E) Total number of rearing behaviors. Values represent mean ± SD. ***, p<0.001, **, p<0.01 and *, p<0.05 by paired Student's t test between Wt mice and Snap25S187A/S187A mice.