posted on 2010-04-22, 00:57authored byTale Sliedrecht, Chao Zhang, Kevan M. Shokat, Geert J. P. L. Kops
A–C: Time-lapse analysis by DIC microscopy of mitotic progression of HCT-derived (A, B) and UTR-derived (C) cells treated with DMSO or 23dMB-PP1. Images in A display morphology of HCT-derived cells imaged at the indicated timepoints after NEB (nuclear envelope breakdown). Graphs in B and C show cumulative percentages of cells that display first signs of furrowing at indicated times after NEB. Dashed lines indicate half-time to furrowing.