posted on 2013-01-28, 00:06authored byM. Dominik Fischer, Tobias Goldmann, Christine Wallrapp, Regine Mühlfriedel, Susanne C. Beck, Gabi Stern-Schneider, Marius Ueffing, Uwe Wolfrum, Mathias W. Seeliger
MicroBeads are alginate spheres with a diameter about 180 µm. (A) They may be used for a sustained release of therapeutic proteins while the producing cell population is protected from humoral and cellular immune response mechanisms. (B) For this study, beads with human mesenchymal stem cells were used that (C) express eGFP as reporter protein, which allowed to monitor localization, distribution and viability of MicroBeads in vivo.