Methylation of FBP1 promoter in human liver and colon cancer.
figure
posted on 2013-02-20, 12:34 authored by Mingquan Chen, Jianbin Zhang, Ning Li, Zhiping Qian, Mengqi Zhu, Qian Li, Jianming Zheng, Xinyu Wang, Guangfeng Shi(A) Schematic structure of the FBP1 CGI, with the exon 1 and MSP and BGS region indicated. Each short vertical line represents one CpG site. The position of MSP primers were marked as arrows. The methylation status of the FBP1 CGI was analyzed by MSP (B) and BGS (C). MSP = Methylation-specific PCR; USP = Unmethylation-specific PCR. For BGS in (C), each circle indicates one CpG site and circles filled in black represent methylated CpG sites. One row of circles represents a single colony.
