Maximum likelihood phylogeny of the TIR domain of the TLR adaptor molecules alone is consistent with the topology observed in Figure 1.
figureposted on 11.01.2013, 02:44 by Jeffrey M. Roach, Luigi Racioppi, Corbin D. Jones, Anna Maria Masci
The tree is rooted by the outgroup TIR domain of Homo sapiens TLR5. The numbers indicate boot-strap support out of 1000. Only values above 500 are indicated.