The existence of more than 30 paralogous genes located within the flanking regions of the ACD1 and ACD6 clusters (marked in grey) suggests a large-scale (>18 Mb) segmental duplication between chromosome 1 (HSA 1, p-arm) and chromosome 6 (HSA 6, p- and q-arms). Each line connects two paralogous genes. Ideograms of both chromosomes are displayed, where dark and white bands represent G and R bands, respectively. Indicated chromosome coordinates serve as a guide to positioning the duplicated segment.