Kinetics of loop DNA digestion with DNase I in nucleoids from P0, P7, P80 and P540 rat neurons.

Nucleoids were treated with DNase I at 0.92 U/ml. Each time-point value corresponds to the average of independent experiments using separate animals as the source of nucleoids (P0 n = 4; P7 n = 5; P80 n = 5; P540 n = 4). The data sets for P7 and P540 were taken from our previous work [21]. The topological zones relative to the NM for the corresponding kinetics were established considering the local slopes between pairs of time points (Table 3) and the corresponding S.D.