Figure_6.tif (81.83 kB)
Involvement of PI3K in the up-regulation of HO-1 by MALP-2.
figure
posted on 2014-07-31, 03:00 authored by Xiaoxing You, Liangzhuan Liu, Yanhua Zeng, Ranhui Li, Jun He, Xiaohua Ma, Chuanhao Jiang, Cuiming Zhu, Liesong Chen, Minjun Yu, Guangli Ou, Yimou WuA. Cells were stimulated with MALP-2 for the indicated time intervals, the cell lysates were subjected to Western blotting using an anti-p-Akt antibody. B. THP-1 cells were pretreated with LY294002 (25 µM) for 1 h, and then incubated with 5 ng/ml MALP-2 for another 16 h. Densitometric analysis was performed after normalization with total Akt or β-actin. All of the values are expressed as means ± SEM of three independent experiments. *, P<0.05 for comparisons within groups.