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Intracellular distribution of AChE activity in the 3 types of cellular morphology.

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posted on 20.02.2013, 05:37 by Laura E. Sperling, Janine Klaczinski, Corina Schütz, Lydia Rudolph, Paul G. Layer

Cell morphology, particularly so neurite lengths are altered as a result of AChE overexpression and culture on laminin-1. Pictures show merged view of Karnovsky Roots (brown), immunostaining with an anti-alpha tubulin antibody (green) and cell nuclei stained with DAPI (blue). Scale bar 50 µm. Table: AChE overexpression stimulates the formation of type III morphology (neuronal-like). Laminin-1 leads to a strong shift to the type I and type II cells.

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