Increased discriminatory activity of Fpr2/3^-/- mice in the novel object recognition test.

The bar graph in A shows the total time (seconds) spent exploring the objects used in the test (shown in the top picture) during the 10-minute acquisition phase (left panel) and the % of time spent on the novel object (shown in the bottom picture) in the subsequent 5-minute test phase (right panel). The bar graphs in B show the total number of arm entries and spontaneous alternation percentage (calculated as described in material and Methods section) in the Y-maze during a 5-minute trial. Values are expressed as median ± S.E.M. and representative of n = 4 different experiments involving 6–9 mice per group. ** P<0.05 indicates significant values compared with wild-type (WT) control mice (Mann–Whitney U-test).