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Immunohistochemical staining of AGEs in the hippocampus and cortex.

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posted on 2013-02-20, 15:01 authored by Chanshuai Han, Yang Lu, Yan Wei, Ying Liu, Rongqiao He

Mice were injected (i.p.) with Rib at dose of 2 g/kg, or Glc at dose of 2 g/kg, or 0.9% saline (controls) for 30 days. AGEs in the mouse brain were detected by immunohistochemistry using anti-AGEs monoclonal antibody. The areas outlined with dashed lines are magnified in the lower panels (bar  =  50 µm).

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