IgG and complement C3 deposition at the basement membrane in experimental bullous pemphigoid.
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posted on 2012-02-06, 01:45 authored by Eva Oswald, Alina Sesarman, Claus-Werner Franzke, Ute Wölfle, Leena Bruckner-Tuderman, Thilo Jakob, Stefan F. Martin, Cassian SitaruIF microscopy, performed on frozen sections of a perilesional mouse skin biopsy reveals linear deposition of (A) rabbit IgG, (B) murine C3, and (C) murine IgG at the epidermal basement membrane in a diseased mouse. No deposits of (D) rabbit IgG, (E) murine C3, and (F) murine IgG of a control mouse showing no skin lesions (magnification, ×400).
