IQGAP1 regulates cell proliferation and migration ability.
figure
posted on 2015-08-07, 04:02 authored by Xuewen Jin, Yuling Liu, Jingjing Liu, Weiliang Lu, Ziwei Liang, Dan Zhang, Gang Liu, Hongxia Zhu, Ningzhi Xu, Shufang Liang<p>Overexpression of IQGAP1 in HepG2 cells enhanced cell proliferation (A) and cell migration (C, D). Knockdown of IQGAP1 decreased cell growth (B) and migration (E, F). Control: HepG2 cells transfected with empty pCMV6 plasmids; flag-IQ:HepG2 cells transfected with pFlag-IQGAP1 plasmids. siNC: HepG2 cells transfected with control siRNA; si-IQ: HepG2 cells transfected with IQGAP1 siRNA. Scale bar represents 100 μm (original magnification×200).</p>
