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Histological analysis of CCl4-induced chronic liver injury.

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posted on 2014-10-13, 03:43 authored by Pradeep Kumar, Tekla Smith, Khalidur Rahman, Natalie E. Thorn, Frank A. Anania

A) Representative H&E stained liver section are shown. B) Representative Sirius Red staining liver sections obtained from control (saline group) revealed normal lobular structure while in CCl4-gavaged mice liver sections reveal extensive collagen deposition and bridging fibrosis. The degree of collagen deposition was significantly decreased in CCl4–ADN treated mice (N = 5 mice/cohort).

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