Histologic sections of the hind paw, stained with Gömöri trichrome staining (a) and Hematoxylin-eosin (b-d) (photographed at 40x magnification).

Tissue exposed to 25% DMSO (control; a), and complex 5 (b) with the massive acute inflammatory reaction in the transition from dermis to hypodermis with the massive infiltrate of neurophils (PMN) in connective tissues; tissue exposed to complex 9 (c) with the massive acute inflammatory reaction reaching from the hypodermis up to the papillary layer of dermis with a massive infiltrate of neurophils (PMN); tissue exposed to Auranofin (d) with the inflammatory reaction in the hypodermis with a slight PMN infiltrate. 1 - PMN infiltrate, 2 - arteriola, 3 - dilated veins with haemostasis, 4 - vein with PMN presence in the blood stream and haemostasis, 5 - collagen connective tissue, 6 - haemorrhage characterised by the presence of erythrocytes in interstitium, 7 - muscle fibres.