Fig_3.tif (2.38 MB)
Heatmap visualization of the DNA methylation of 44 differentially methylated CpGs (DMCs) on Chromosome 13, 18 and 21.
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posted on 2015-07-31, 02:53 authored by Lotte Hatt, Mads M. Aagaard, Jesper Graakjaer, Cathrine Bach, Steffen Sommer, Inge E. Agerholm, Steen Kølvraa, Anders BojesenRows represent CpG targets, columns represent samples. Each cell is colored according to the level of methylation (β-value).Blue; low β-values, yellow; intermediate β-values, red; high β-values.
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methylation statusrestriction sitesaneuploidy testingbeadchip microarray study450.000 CpG sitesMSRENew Epigenetic Biomarkersblood sampleCpG sitesDNA methylation profileschorionic tissueblood samples12 1 st trimesters chorionic samplesBlood cellsBlood circulationplacental DNAdifferentially methylated CpG sitesduplication syndromesdifferentially methylatednipd
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