Gene expression profiles at 15 months post-implantation.

Histograms representing enriched Gene Ontology terms for clusters 1, 3, 4 (green and red bars) and 2 (blue bars). P-value ≤0,05 (A). Gene interaction network derived from STRING database analysis of up- and down-regulated genes on A.L. tissues (clusters 1, 3, 4). Pink nodes with grey border connect elements between up- or down-regulated nodes in analyzed clusters. Central color node: gene expression in A.L. tissues; border: B.L. tissues. Yellow edges link connected nodes, while blue edges those altered in analyzed clusters. Purple gene names represent relevant nodes according to Centiscape algorithm. *Genes discussed in the text (B).