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GSEA Enrichment Plots of GO Molecular Functions and KEGG Canonical Pathways With the Largest Normalized Enrichment Scores.

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posted on 2012-08-03, 02:18 authored by Jonathan J. Hansen, Yong Huang, Daniel A. Peterson, Laura Goeser, Ting-Jia Fan, Eugene B. Chang, R. Balfour Sartor

(A) Receptor Activity (GO0004872), (B) Structural Constituent of Ribosome (GO0003735), (C) Hydrogen Ion Transporting ATPase Activity (GO0046961), (D) Ribosome, (E) Oxidative Phosphorylation, (F) Pyrimidine Metabolism. Top portions of the plots show the running enrichment score for the gene set as the analysis “walks down” the ranked list. Middle portions of the plots shows where members, indicated by vertical black lines, of the gene set appear in the ranked list of genes. Bottom portions of the plots show the value of the ranking metric as one progresses down the list of ranked genes.

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