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Functional analysis of Cre activity in the Bapx1ICIE;Rosa26R and Bapx1FCFE;Rosa26R mice.

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posted on 2011-12-21, 00:21 authored by Hsiao Yun Chan, V. Sivakamasundari, Xing Xing, Petra Kraus, Sook Peng Yap, Patricia Ng, Siew Lan Lim, Thomas Lufkin

(a–c) Whole-mount E12.5 Bapx1ICIE;Rosa26R and Bapx1FCFE;Rosa26R embryos stained with X-gal showing β-galactosidase activity in the correct anatomical context of Bapx1. (d–f) Transverse sections of E11.5 embryos confirmed X-gal stained cells in the mesenchymal cells of the midgut and not in the endothelium. MC, Meckel's cartilage; LM, limb mesenchyme; VC, vertebral column; R, ribs; M, mesenchyme; E, endothelium.

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