Force distance indentation curves.

Comparison of experimental values reported for empty SubE mutants of CCMV [57] (black) and computed values from simulations with an ELNEDYN elastic network with a uniform spring constant of 200 kJ mol⁻¹nm⁻² (blue) and a IDEN elastic network (green). Forces obtained for forward (solid lines) and backward (dashed lines) indentation. The reported forces are average values over the whole 1 ns simulation time of a step and the shaded areas correspond to their respective standard deviation.