Fluid mechanics parameters of flow in mouse great arteries.

a) Reynolds numbers of flow in specific arteries, averaged along the entire arterial centerline, at different developmental stages. DAo: descending aorta; AAo: ascending aorta and aortic arch; PT: pulmonary trunk including the ductus arteriosus. b) Peak flow streamlines in the great arteries of embryonic mouse at E14.5 (left) and fetal mice at E17.5 (right). c) Normalized helicity iso-surfaces in the flow in great arteries of embryonic and fetal mice of various developmental stages, showing the development of classical Dean flow in the great arteries. There was a general increase helicity over age, and equal intensity in right-handed (red, normalized helicity = 0.2) and left-handed (blue, normalized helicity = −0.2) helical structures.