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FH535 reduces cyclin D1 and survivin mRNA levels in LCSC and in HCC cell lines.

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posted on 2014-06-18, 03:58 authored by Roberto Gedaly, Roberto Galuppo, Michael F. Daily, Malay Shah, Erin Maynard, Changguo Chen, Xiping Zhang, Karyn A. Esser, Donald A. Cohen, B. Mark Evers, Jieyun Jiang, Brett T. Spear

LCSCs, Huh7 and Hep3B cells were treated with DMSO alone or increasing concentrations of FH535 for 38-time PCR for expression of Cyclin D1 (Panel A) or Survivin (Panel B). In both cases, mRNA levels were plotted relative to β2-microglobulin. The experiment was done twice with similar results.

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