Figure_4.tif (2.01 MB)
Expression of CXC chemokine receptor 4 (CXCR4) and von Willebrand Factor (vWF) in c-kit+ cells.
figure
posted on 2014-02-24, 03:32 authored by Daniela Farkas, Donatas Kraskauskas, Jennifer I. Drake, Aysar A. Alhussaini, Vita Kraskauskiene, Harm J. Bogaard, Carlyne D. Cool, Norbert F. Voelkel, Laszlo FarkasRepresentative optical sections obtained by confocal microscopy demonstrating the co-expression of CXCR4, vWF and c-kit in the pulmonary artery wall of a naïve animal and in pulmonary vascular lesion cells of animals with SU541/chronic hypoxia (SuHx) induced severe PAH. The inserts show the area outlined by a box in more detail. Arrows indicate triple positive cells in the inserts. Nuclear counterstaining: 4’-6-diamidino-2-phenylindole (DAPI). Magnification: 400×. Scale bar: 20 µm.
