posted on 2015-04-08, 04:12authored bySundaram A. Vishwanathan, Monica R. Morris, Richard J. Wolitski, Wei Luo, Charles E. Rose, Dianna M. Blau, Theodros Tsegaye, Sherif R. Zaki, David A. Garber, Leecresia T. Jenkins, Tara C. Henning, Dorothy L. Patton, R. Michael Hendry, Janet M. McNicholl, Ellen N. Kersh
A. Lubricant induces rectal shedding of epithelial cells. Examples of epithelial sloughing in a control- (top left) and lubricant-treated animal (top right). The lower panel shows a representative H&E stain of sloughed rectal epithelial cells (20x); B. Blood associated with rectal washes; photographs of microfuges containing rectal lavages; C,D. Epithelial sloughing measured at acute time points collected after the 2nd weekly lubricant application (C), and those measured over the entire study (D). The panel D in this figure shows three collections per week (day 1, pre-lubricant; day 2 pre-lubricant; day 2 post-lubricant), as indicated in Fig. 1.