Elevated Plus Maze (EPM).

(A) Time spent in the open arms. Time spent in the open arms of the JS (n = 29) group was significantly shorter than that of the Naïve (n = 31) and JS+EE (n = 30) groups. There was no significant difference between JS+EE and Naïve groups. (B) The locomotor activity in the EPM. The line crossing in the open arms of the JS group was significantly lower than that of the JS+EE group. Line crossing in the closed arms of the JS+EE group was significantly higher than that of the Naïve and JS groups. Total line crossing of the JS+EE group was significantly higher than that of the Naïve and JS groups. *significantly different from all other groups (p<0.05); &significantly different from JS+EE group (p<0.05); #significantly different from Naïve group (p<0.05).