Effects of disruption of the LPS signaling pathway on counter-regulatory response to hypoglycemia.

Norepinephrine levels in A) serum of wild type and CD14-ko 26 week old mice on ND following injection i.p. with insulin (1–1.5 U/kg body weight) *p<0.05, n = 6; B) urine collected over a 24 h period ***p<0.001, n = 8). C) Area under the curve of the glucose excursions for WT and CD14-ko mice following saline or propranolol (2 mg/kg of body weight) injection 30 minutes prior to insulin tolerance tests. **p<0.01 n = 4 for each group. Statistical differences were determined by student t-tests.