Effect of adenosine receptor A2A antagonist (ZM241385) and adenylyl cyclase inhibitor (SQ22536) on ADP-induced platelet aggregation.
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posted on 2014-11-13, 03:44 authored by Eduardo Fuentes, Jaime Pereira, Diego Mezzano, Marcelo Alarcón, Julio Caballero, Iván PalomoPRP suspension was incubated with ADP, adenosine or inosine plus ADP or pretreated with SQ22536 or ZM241385 for 3 min, followed by addition of adenosine or inosine and ADP. The graph depicts the mean ± SEM of n = 6 experiments. ***p<0.001. The results presented are from 6 separate volunteers (each donors performed as single triplicates).
