Decrease in the relative protein expression of SRBI and LDLR in female apoD−/− mice but opposite pattern for mRNA expression.
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posted on 2014-12-30, 03:21 authored by Kamilah Ali, Ehab M. Abo-Ali, M. D. Kabir, Bethany Riggins, Susanna Nguy, Lisa Li, Ujala Srivastava, Su Mya Mya ThinnLiver levels of A) Cholesterol and B) Triglyceride C) Relative expression of genes and D) Protein expression levels of LDLR and SRBI after 12 weeks on a Western diet. n = 5–7 per group, mean±SD, *p<0.05, **p<0.01.
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lipid disordersplasma lipidapoD deficiencyWT micecatabolic ratelipoprotein profilesLDL particles12 weeksplasma apoD levelsinvivo HDL metabolism experimentC 57BL backgroundplasma HDLplasma levelsHDL cholesteryl esterapoB levelsC 57BL miceHDL particlesplasma phospholipid transfer protein activityLDLR protein levelsHDL metabolism.MethodsLDL receptorsapoAI levels
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