DVD-Ig proteins inhibit HRG binding to FaDu cells.
figure
posted on 2015-05-21, 03:20 authored by Jinming Gu, Jinsong Yang, Qing Chang, Zhihong Liu, Tariq Ghayur, Jijie GuSerial dilutions of HRG were incubated with 100 nM anti-EGFR and anti-ErbB3 mAbs alone, anti-EGFR and anti-ErbB3 mAbs in combination, the bsAb, or anti-EGFR/ErbB3 DVD-Ig proteins. HRG binding affinity to FaDu cells was measured via FACS. MFI: median fluorescence intensity. The error bars indicate standard deviation from the mean.
