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Copper deficiency leads to anemia in mice.

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posted on 2013-03-29, 19:49 authored by Pavle Matak, Sara Zumerle, Maria Mastrogiannaki, Souleiman El Balkhi, Stephanie Delga, Jacques R. R. Mathieu, François Canonne-Hergaux, Joel Poupon, Paul A. Sharp, Sophie Vaulont, Carole Peyssonnaux

(A) Postnatal CuD regime and i.p copper repletion experimental design. (B) Hematological indices of mice at P45 post i.p injection of copper. (C) Plasma iron and copper concentrations. (D) Liver Hamp1 mRNA levels. mRNA values were adjusted to 1. (E) Liver iron and copper concentrations. (F) Duodenal iron and copper concentrations. 1-way ANOVA with Newman-Keuls posthoc testing. Data are presented as means±SEM: CTR (n = 6), CuD (n≥4), CuD +CuSO4 (n≥4). Means without a common letter or symbol differ (p<.05).

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