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Comparison of trimer junction of M. tuberculosis and P. furiosus ferritins.

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posted on 2013-02-20, 19:25 authored by Garima Khare, Vibha Gupta, Prachi Nangpal, Rakesh K. Gupta, Nicholas K. Sauter, Anil K. Tyagi

(A) The surface representation of 3 subunits of BfrB at the 3-fold junction when viewed from inside of the molecule to illustrate the effect of its extended C-terminus. The arrangement of residues, Q126 and S171 (stick representation) involved in formation of the channel mouth are shown in the inset. (B) Surface representation of similar region in Pyrococcus furiosus where the pore is constituted by E121 (towards the ferroxidase centre) and N125 (towards inner core).

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