Comparison of the Bayesian method to the delta-delta-Ct method, reanalyzing data from [38].

(a) Fold-changes inferred by the naïve, informed and “classic” models plotted against fold-changes derived by the delta-delta-Ct analysis with a single control gene. (b) Comparison of p-values derived by the Bayesian z-test from naïve, informed, and “classic” models (see legend on panel a) with p-values obtained by pairwise t-tests within the delta-delta-Ct pipeline. On both panels, the line denotes 1∶1 correspondence. On panel b, points above the line indicate higher power (lower p-values) of the new models.