Figure_3.tif (5.25 MB)
Comparison between ESR1 and ER protein on Yale breast cancer cohorts.
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posted on 2013-02-20, 05:18 authored by Jennifer M. Bordeaux, Huan Cheng, Allison W. Welsh, Bruce G. Haffty, Donald R. Lannin, Xingyong Wu, Nan Su, Xiao-Jun Ma, Yuling Luo, David L. RimmThe natural log of the nuclear ER AQUA score determined by QIF using SP1 is shown on the y-axis and the AQUA score for ESR1 determined by qISH is on x-axis for YTMA 128, n = 167 with scores for both SP1 and ESR1 (A) and YTMA 130 1993–2005 Subset, n = 195 with scores for both SP1 and ESR1 (B). The dotted line represents the threshold for ER protein positivity. (C) Representative images from 4 cases on YTMA 128 for cytokeratin (green), DAPI (blue), and ESR1 or ER SP1 (red).
