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Comparative IC50 values of various anticancer drugs in 2D and 3D culture system.

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posted on 2013-01-18, 01:34 authored by Chandraiah Godugu, Apurva R. Patel, Utkarsh Desai, Terrick Andey, Alexandria Sams, Mandip Singh

A) Cytotoxicity of various anticancer drugs (Cisplatin, Gemcitabine, 5-Fluorouracil and Camptothecin) in 2D H1650 parental and stem cells. B) Cytotoxicity of various anticancer drugs in 3D alginate scaffold systems on H1650 parental, C) H1650 stem cells. D) Comparative cytotoxicity IC50 values of various anticancer drugs in 3D alginate scaffold systems on H1650 parental and stem cells. Each data point is represented as mean ± sem (n = 4–6). *<0.05, **P<0.01 and ***P<0.001 Vs respective H1650 parental cell groups.

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