Chromosomal location of the T1 TIGRE locus.
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posted on 2008-05-09, 00:41 authored by Hongkui Zeng, Kyoji Horie, Linda Madisen, Maria N. Pavlova, Galina Gragerova, Alex D. Rohde, Brian A. Schimpf, Yuqiong Liang, Ethan Ojala, Farah Kramer, Patricia Roth, Olga Slobodskaya, Io Dolka, Eileen A. Southon, Lino Tessarollo, Karin E. Bornfeldt, Alexander Gragerov, George N. Pavlakis, George A. Gaitanaris(A) Genomic sequences surrounding the T1 TIGRE locus. The underlined AAAG sequence was duplicated upon viral integration and the viral TIGRE vector was inserted exactly in between the duplication. (B) BLAT search of the UCSC Mouse Genome Browser (http://genome.ucsc.edu/cgi-bin/hgBlat) with genomic sequences (as in (A)) surrounding T1 revealed the localization of T1 locus to chr9 qA3. This panel is a screen shot of the BLAT search result. The location of the sequences used for the search is indicated by a vertical bar next to “YourSeq”. The insertion site is in between two genes: AB124611 and Carm1 (alternative name Prmt4), and does not seem to disrupt either gene.
