posted on 2015-08-24, 03:08authored byBryan M. Zhao, Sarah L. Keasey, Joseph E. Tropea, George T. Lountos, Beverly K. Dyas, Scott Cherry, Sreejith Raran-Kurussi, David S. Waugh, Robert G. Ulrich
A total of 29 signaling pathways were identified in the subset of significant peptides recognized by a group of 10 phosphatases. Each phosphatase, as well as its corresponding edges, is color coded. Pathway node size corresponds to number of peptides belonging to that pathway cluster, while edge weight corresponds to the number of peptides in the pathway cluster recognized by the phosphatase. Pathway nodes that are over-represented when compared to a background list encompassing all peptides on the microarray (p<0.001515) are shown in white, while all other pathway nodes are grey.