Figure_6.tif (578.81 kB)
Cd-elevated [Ca2+]i induces ROS in neuronal cells.
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posted on 2013-02-20, 19:02 authored by Baoshan Xu, Sujuan Chen, Yan Luo, Zi Chen, Lei Liu, Hongyu Zhou, Wenxing Chen, Tao Shen, Xiuzhen Han, Long Chen, Shile HuangIndicated cells were exposed to 0–20 µM Cd for 24 h after pretreatment with/without indicated concentrations of BAPTA/AM (A) or EGTA (B) for 30 min, followed by ROS detection, as described in Materials and Methods. Results are presented as mean ± SE; n = 6. aP<0.05, bP<0.01, difference vs. control group; cP<0.01, difference vs. 10 µM Cd group; dP<0.01, difference vs. 20 µM Cd group.