Figure_1.tif (155.9 kB)
Capsaicin sensitizes heat-evoked foot withdrawal to heat in mice, but not naked mole-rats.
figure
posted on 2013-02-20, 21:47 authored by Antje Brand, Ewan St. J. Smith, Gary R. Lewin, Thomas J. ParkLatencies were measured every 10 minutes in mice (A, n = 6) and naked mole-rats (B, n = 6). Saline (i.t., gray traces) or capsaicin (1 mM topical, red traces) were given after the first three time points (black arrows). Whereas saline had no effect upon withdrawal latency in either species, capsaicin induced faster foot withdrawal in mice (A), but had no effect upon naked mole-rats (B).