Canonical correlation analysis of RNA and protein temporal expression profiles.
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posted on 2012-03-29, 00:34 authored by Katrina M. Waters, Tao Liu, Ryan D. Quesenberry, Alan R. Willse, Somnath Bandyopadhyay, Loel E. Kathmann, Thomas J. Weber, Richard D. Smith, H. Steven Wiley, Brian D. ThrallA) Ranked canonical correlations between RNA expression and protein expression, compared with random permutations. Each gray line shows the computed canonical correlations for a single random permutation. The first observed canonical correlation exceeds all corresponding permuted values, and the second canonical correlation exceeds 99% of permuted values; both are considered statistically significant. B) Scatter plot of first canonical variable between RNA and protein expression for 199 gene/protein pairs with a correlation coefficient of 0.44.
