CSF NfH in ALS and controls.
Box and dot plots show CSF NfHSMI35 in ALS, Parkinson's disease (PD), and controls (CTRL). ALS fast = patients with rapid progression of disease over follow-up of 6 months, ALS slow = patients with slow progression of disease over follow-up. The box represents the 25th to 75th quartile, the whiskers represent the range, and the horizontal line in the box represents the median. Difference between the groups was significant (p<0.001, Kruskal-Wallis Analysis of Variance on Ranks), with post-hoc analysis (Dunn's method) showing patients with ALS to have significantly higher CSF concentrations as compared to patients with PD and controls (p<0.05 each).