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CO6-MMP serum levels in BDL-rats.

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posted on 2013-02-20, 14:52 authored by Sanne Skovgård Veidal, Morten Asser Karsdal, Efstathios Vassiliadis, Arkadiusz Nawrocki, Martin Røssel Larsen, Quoc Hai Trieu Nguyen, Per Hägglund, Yunyun Luo, Qinlong Zheng, Ben Vainer, Diana Julie Leeming

BDL rat liver fibrosis model. Serum CO6-MMP was assessed in BDL and sham operated rats at termination. Termination time points were 2 and 4 weeks after surgery. Levels of CO6-MMP were significantly elevated in BDL rats compared to sham levels at both the two-( mean BDL 29.5 ng/mL, mean sham: 14.2 ng/mL, p = 0.0001) and four week mean BDL: 33.0 ng/ml, (mean sham: 11.8 ng/mL, p = 0.0003) termination point.

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