CCND1 and RSF-1 gene amplification by FISH.
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posted on 2013-12-19, 03:31 authored by Dana Keilty, Marguerite Buchanan, Katerina Ntapolias, Olga Aleynikova, Dongsheng Tu, Xiao Li, Lois Shepherd, Vivien Bramwell, Mark BasikImages (100X magnification) of FISH for CCND1 (A) and RSF-1 (B) on two different breast tumor samples from the MA.12 tissue microarray. Sample A shows CCND1 gene amplification while sample B shows RSF-1 amplification. Green dots are centromeric probes for chromosome 11, while red dots represent the gene probes. Counterstaining is with DAPI II.
