BDNF haplotype block structure.
figure
posted on 2013-02-20, 11:51 authored by Elham Rostami, Frank Krueger, Serguei Zoubak, Olga Dal Monte, Vanessa Raymont, Matteo Pardini, Colin A. Hodgkinson, David Goldman, Mårten Risling, Jordan GrafmanBDNF haplotype block structure. The numbers within the diamonds are D' values representing linkage disequilibrium between SNP pairs. Only values of D'<98 are present so the solid red diamonds represent absolute LD (D' = 1) and the grey diamonds represent high probability or evidence of historical recombination. Two short sub-blocks of 4 kb and 13 kb long were determined with use of Haploview software and used for detailed analysis. The blocks are defined using the pairs of SNPs with an LD >0.85. Note that BDNF gene is located on minus DNA strand.
