Anti-ErbB2 DVD-Ig proteins inhibit cell proliferation.

(A) Calu-3, (B) MDA-MB-175 VII, and (C) N87 cells were treated with indicated dosages of DVD-Ig proteins, mAbs, or combination for 96 hrs. Cell proliferation was measured with ³H thymidine incorporation assays as described in Materials and Methods. Three independent experiments with triplicates were performed. One representative experiment is shown here. The error bars indicate standard deviation from the mean.