Alignment of the amino acid sequence deduced for RNRS1 and its homologues.

The α helix and loop regions were shown in blue and black, respectively. The conserved sites of 171- and 229-amino acid residue are shown in red. Information of reference sequence are as follows: RNRS, small subunit of ribonucleotide reductase 1; 3vpn, A ribonucleoside-diphosphate reductase subunit M2; 3vpo, A ribonucleoside-diphosphate reductase subunit M2; 3olj, A ribonucleoside-diphosphate reductase subunit M2; 1xsm, A ribonucleoside reductase R2; 2vux, A ribonucleoside-diphosphate reductase subunit M2 B; 4djn, A ribonucleoside-diphosphate reductase subunit M2 B; 2p1i, A ribonucleotide reductase, small chain; 1w69, A ribonucleoside-diphosphate reductase M2 chain; 1smq, A ribonucleoside-diphosphate reductase small chain 1; 2uw2, A ribonucleoside-diphosphate reductaseM2 subunit; 3hf1, A ribonucleoside-diphosphate reductase subunit M2 B; 1jk0, A ribonucleoside-diphosphate reductase small chain 1.