AQP2 excretion during urinary concentration test.

For the urinary concentration test, urinary AQP2 excretion and osmolality were measured on samples obtained hourly after 20 µg intranasal DDAVP administration. AQP2 urinary excretion. (A) In normocalciuric children, DDAVP administration resulted in a significant increase in urinary AQP2 excretion. Hypercalciuric children had a high basal AQP2 excretion and DDAVP administration did not result in a significant increase in urinary AQP2 excretion. Data were analyzed by Wilcoxon Signed Rank ANOVA test for paired non parametric data (*p = 0.0023). (B) Comparison of basal AQP2 excretion in hypercalciurics and normocalciurics. patients. In hypercalciurics a significant higher AQP2 excretion was observed (p = 0.036 ANOVA test).